Directed against Unrelated Enteric Bacterial Tolerance to Prevent T Cell-Mediated Colitis Allows for Ovalbumin-Induced Oral Expression of Dual TCR on DO11.10 T Cells
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منابع مشابه
Memory/effector T cells in TCR transgenic mice develop via recognition of enteric antigens by a second, endogenous TCR.
The majority of clonotypic CD4(+) T cells in the intestinal lamina propria of DO11.10 TCR transgenic mice have an activated/memory phenotype and produce effector cytokines despite the absence of prior exposure to ovalbumin (OVA), the transgene-specific antigen. A small number of splenic T cells have a similar phenotype. Clonotypic T cells from Peyer's patch are intermediate in both phenotype an...
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تاریخ انتشار 2004